منابع مشابه
How do tumors make ends meet?
W Barbara McClintock irradiated strains of Indian corn in the early 30s, she identified ring chromosomes, which she soon realized were a special case of chromosomes broken by radiation; the broken ends sometimes fused to one another and formed a ring (1, 2). This discovery led McClintock to hypothesize the existence of a special structure at the chromosome tip that would maintain chromosome sta...
متن کاملSir-Ku-itous Routes to Make Ends Meet
of telomere-associated Sir proteins. This gives Ku proBarbara McClintock first noticed that the normal ends teins a more prominent role in heterochromatin assemof chromosomes were different from ends created by bly at telomeres than previous models would have prechromosome breakage. We now understand that normal dicted. ends are capped by proteins that bind to the repeating Before turning to th...
متن کاملRepair and Recombination: How to make ends meet
The repair of double-stranded breaks in DNA and the recombination of antibody gene V(D)J segments share a common pathway involving the Ku protein, which binds DNA ends, and its associated protein kinase.
متن کاملHow African doctors make ends meet: an exploration.
This paper is an attempt to identify individual coping strategies of doctors in sub-Saharan Africa. It also provides some indication of the 'effectiveness' of these strategies in terms of income generation, and analyses their potential impact on the functioning of the health care system. It is based on semi-structured interviews of 21 doctors working in the public health sector in sub-Saharan A...
متن کاملThe Direct Measurement of Welfare Levels : How Much Does It Cost to Make Ends Meet ?
We adopt a direct approach to measuring the welfare levels of households with different incomes and varying characteristics by using households' responses to subjective questions about their evaluations of their own economic status. We use this approach to analyze newly available u.S. data on subjective well-being. We address such interrelated questions as how to rank households by welfare leve...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1999
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.96.5.1826